| Primary | |||||||||||||||||||
| Salary | Name | P | AVG | OBP | SPC | G | AB | H | 2B | 3B | HR | R | RBI | BB | K | HBP | IW | SB | CS |
| 9 | Snow* | 1b | .327 | .429 | .529 | 107 | 346 | 113 | 32 | 1 | 12 | 62 | 60 | 58 | 61 | 7 | 0 | 4 | 0 |
| 10 | Closser# | c | .319 | .364 | .398 | 36 | 113 | 36 | 6 | 0 | 1 | 5 | 10 | 6 | 22 | 2 | 0 | 0 | 0 |
| 18 | Guillen,C# | ss | .318 | .379 | .542 | 136 | 522 | 166 | 37 | 10 | 20 | 97 | 97 | 52 | 87 | 2 | 3 | 12 | 5 |
| 21 | Hafner* | dh | .311 | .410 | .583 | 140 | 482 | 150 | 41 | 3 | 28 | 96 | 109 | 68 | 111 | 17 | 7 | 3 | 2 |
| 26 | Lee,C | lf | .305 | .366 | .525 | 153 | 591 | 180 | 37 | 0 | 31 | 103 | 99 | 54 | 86 | 7 | 3 | 11 | 5 |
| 8 | Gonzalez,LA | 2b | .292 | .330 | .469 | 102 | 322 | 94 | 17 | 2 | 12 | 42 | 40 | 15 | 67 | 4 | 1 | 1 | 5 |
| 18 | Holliday | lf | .290 | .349 | .488 | 121 | 400 | 116 | 31 | 3 | 14 | 65 | 57 | 31 | 86 | 6 | 0 | 3 | 3 |
| 12 | Inge | 3b | .287 | .340 | .453 | 131 | 408 | 117 | 15 | 7 | 13 | 43 | 64 | 32 | 72 | 4 | 0 | 5 | 4 |
| 15 | Piazza | 1b | .266 | .362 | .444 | 129 | 455 | 121 | 21 | 0 | 20 | 47 | 54 | 68 | 78 | 2 | 14 | 0 | 0 |
| 10 | Infante | 2b | .264 | .317 | .449 | 142 | 503 | 133 | 27 | 9 | 16 | 69 | 55 | 40 | 112 | 1 | 3 | 13 | 7 |
| 10 | Werth | lf | .262 | .338 | .486 | 89 | 290 | 76 | 11 | 3 | 16 | 56 | 47 | 30 | 85 | 4 | 0 | 4 | 1 |
| 1 | Youkilis | 3b | .260 | .367 | .413 | 72 | 208 | 54 | 11 | 0 | 7 | 38 | 35 | 33 | 45 | 4 | 0 | 0 | 1 |
| 15 | Pena,W | rf | .259 | .316 | .527 | 110 | 336 | 87 | 10 | 1 | 26 | 45 | 66 | 22 | 108 | 6 | 1 | 5 | 2 |
| 13 | Koskie* | 3b | .251 | .342 | .495 | 118 | 422 | 106 | 24 | 2 | 25 | 68 | 71 | 49 | 103 | 12 | 10 | 9 | 3 |
| 3 | Lopez,F# | ss | .242 | .314 | .405 | 79 | 264 | 64 | 18 | 2 | 7 | 35 | 31 | 25 | 81 | 3 | 0 | 1 | 1 |
|   | Pitchers |   | .196 | .232 | .275 | 0 | 189 | 37 | 10 | 1 | 1 | 9 | 13 | 8 | 54 | 1 | 0 | 0 | 0 |
|   | Total |   | .282 | .354 | .484 | 0 | 5851 | 1650 | 348 | 44 | 249 | 880 | 908 | 591 | 1258 | 82 | 42 | 71 | 39 |
| Secondary | ||||||||||||||||
| Name | P | GS | PA | SH | SF | GDP | GW | CI | OPS | RC | RC27 | ISO | TAVG | SEC | EBH | TB |
| Snow* | 1b | 88 | 417 | 2 | 4 | 5 | 9 | 0 | .958 | 85.1 | 9.4 | .202 | 1.059 | .382 | 45 | 183 |
| Closser# | c | 29 | 124 | 3 | 0 | 3 | 1 | 0 | .762 | 16.1 | 5.2 | .080 | .663 | .133 | 7 | 45 |
| Guillen,C# | ss | 133 | 583 | 3 | 4 | 12 | 8 | 0 | .921 | 106.6 | 7.6 | .224 | .936 | .337 | 67 | 283 |
| Hafner* | dh | 131 | 576 | 0 | 6 | 11 | 13 | 3 | .993 | 118.5 | 9.1 | .272 | 1.070 | .415 | 72 | 281 |
| Lee,C | lf | 153 | 658 | 0 | 6 | 10 | 11 | 0 | .891 | 114.7 | 7.2 | .220 | .897 | .321 | 68 | 310 |
| Gonzalez,LA | 2b | 71 | 351 | 9 | 1 | 5 | 1 | 0 | .799 | 47.4 | 5.2 | .177 | .718 | .211 | 31 | 151 |
| Holliday | lf | 109 | 439 | 1 | 1 | 9 | 4 | 0 | .837 | 66.6 | 6.0 | .198 | .794 | .275 | 48 | 195 |
| Inge | 3b | 112 | 458 | 8 | 6 | 4 | 3 | 0 | .793 | 64.7 | 5.6 | .167 | .756 | .248 | 35 | 185 |
| Piazza | 1b | 123 | 528 | 0 | 3 | 14 | 9 | 0 | .806 | 73.1 | 5.6 | .178 | .782 | .327 | 41 | 202 |
| Infante | 2b | 123 | 556 | 7 | 5 | 4 | 5 | 0 | .766 | 73.0 | 5.0 | .185 | .735 | .276 | 52 | 226 |
| Werth | lf | 70 | 326 | 1 | 1 | 1 | 2 | 0 | .825 | 50.7 | 6.3 | .224 | .829 | .338 | 30 | 141 |
| Youkilis | 3b | 54 | 248 | 0 | 3 | 1 | 1 | 0 | .780 | 34.9 | 5.9 | .154 | .788 | .308 | 18 | 86 |
| Pena,W | rf | 85 | 364 | 0 | 0 | 7 | 6 | 0 | .843 | 54.3 | 5.7 | .268 | .814 | .342 | 37 | 177 |
| Koskie* | 3b | 113 | 488 | 0 | 5 | 6 | 8 | 0 | .837 | 74.3 | 6.1 | .244 | .858 | .374 | 51 | 209 |
| Lopez,F# | ss | 65 | 295 | 2 | 1 | 1 | 2 | 0 | .719 | 35.5 | 4.7 | .163 | .673 | .258 | 27 | 107 |
| Pitchers |   | 87 | 226 | 28 | 0 | 2 | 0 | 0 | .507 | 13.4 | 2.0 | .079 | .396 | .122 | 12 | 52 |
| Total |   | 0 | 6637 | 64 | 46 | 95 | 83 | 3 | .838 | 1020.0 | 6.2 | .202 | .825 | .309 | 641 | 2833 |
| vs LHP | ||||||||||||
|   |   | Versus Left-handed Pitchers | ||||||||||
| Name | P | AVG | OBP | SPC | AB | H | 2B | 3B | HR | RBI | BB | K |
| Snow* | 1b | .255 | .379 | .404 | 47 | 12 | 4 | 0 | 1 | 9 | 9 | 10 |
| Closser# | c | .346 | .393 | .385 | 26 | 9 | 1 | 0 | 0 | 1 | 2 | 5 |
| Guillen,C# | ss | .269 | .316 | .457 | 197 | 53 | 13 | 3 | 6 | 35 | 12 | 32 |
| Hafner* | dh | .244 | .364 | .359 | 156 | 38 | 9 | 0 | 3 | 24 | 18 | 38 |
| Lee,C | lf | .308 | .385 | .551 | 156 | 48 | 8 | 0 | 10 | 24 | 19 | 24 |
| Gonzalez,LA | 2b | .268 | .297 | .443 | 97 | 26 | 6 | 1 | 3 | 9 | 4 | 20 |
| Holliday | lf | .237 | .333 | .402 | 97 | 23 | 8 | 1 | 2 | 10 | 13 | 17 |
| Inge | 3b | .327 | .386 | .530 | 168 | 55 | 5 | 4 | 7 | 27 | 16 | 27 |
| Piazza | 1b | .303 | .421 | .494 | 89 | 27 | 5 | 0 | 4 | 15 | 18 | 16 |
| Infante | 2b | .277 | .320 | .452 | 188 | 52 | 8 | 5 | 5 | 20 | 14 | 39 |
| Werth | lf | .290 | .377 | .624 | 93 | 27 | 5 | 1 | 8 | 19 | 13 | 30 |
| Youkilis | 3b | .250 | .386 | .431 | 72 | 18 | 4 | 0 | 3 | 14 | 16 | 12 |
| Pena,W | rf | .302 | .388 | .651 | 86 | 26 | 3 | 0 | 9 | 22 | 9 | 30 |
| Koskie* | 3b | .233 | .322 | .391 | 133 | 31 | 4 | 1 | 5 | 19 | 13 | 43 |
| Lopez,F# | ss | .292 | .333 | .523 | 65 | 19 | 7 | 1 | 2 | 12 | 3 | 18 |
| Pitchers |   | .167 | .237 | .222 | 54 | 9 | 3 | 0 | 0 | 1 | 4 | 14 |
| Total |   | .274 | .352 | .466 | 1724 | 473 | 93 | 17 | 68 | 261 | 183 | 375 |
| vs RHP | ||||||||||||
|   |   | Versus Right-handed Pitchers | ||||||||||
| Name | P | AVG | OBP | SPC | AB | H | 2B | 3B | HR | RBI | BB | K |
| Snow* | 1b | .338 | .437 | .548 | 299 | 101 | 28 | 1 | 11 | 51 | 49 | 51 |
| Closser# | c | .310 | .355 | .402 | 87 | 27 | 5 | 0 | 1 | 9 | 4 | 17 |
| Guillen,C# | ss | .348 | .416 | .594 | 325 | 113 | 24 | 7 | 14 | 62 | 40 | 55 |
| Hafner* | dh | .344 | .433 | .690 | 326 | 112 | 32 | 3 | 25 | 85 | 50 | 73 |
| Lee,C | lf | .303 | .359 | .515 | 435 | 132 | 29 | 0 | 21 | 75 | 35 | 62 |
| Gonzalez,LA | 2b | .302 | .344 | .480 | 225 | 68 | 11 | 1 | 9 | 31 | 11 | 47 |
| Holliday | lf | .307 | .355 | .515 | 303 | 93 | 23 | 2 | 12 | 47 | 18 | 69 |
| Inge | 3b | .258 | .308 | .400 | 240 | 62 | 10 | 3 | 6 | 37 | 16 | 45 |
| Piazza | 1b | .257 | .347 | .432 | 366 | 94 | 16 | 0 | 16 | 39 | 50 | 62 |
| Infante | 2b | .257 | .315 | .448 | 315 | 81 | 19 | 4 | 11 | 35 | 26 | 73 |
| Werth | lf | .249 | .320 | .421 | 197 | 49 | 6 | 2 | 8 | 28 | 17 | 55 |
| Youkilis | 3b | .265 | .356 | .404 | 136 | 36 | 7 | 0 | 4 | 21 | 17 | 33 |
| Pena,W | rf | .244 | .289 | .484 | 250 | 61 | 7 | 1 | 17 | 44 | 13 | 78 |
| Koskie* | 3b | .260 | .351 | .543 | 289 | 75 | 20 | 1 | 20 | 52 | 36 | 60 |
| Lopez,F# | ss | .226 | .308 | .367 | 199 | 45 | 11 | 1 | 5 | 19 | 22 | 63 |
| Pitchers |   | .207 | .230 | .296 | 135 | 28 | 7 | 1 | 1 | 12 | 4 | 40 |
| Total |   | .285 | .354 | .492 | 4127 | 1177 | 255 | 27 | 181 | 647 | 408 | 883 |